Karen Tye, MD
Karen Tye, MD, is a board-certified radiation oncologist who sees people with a variety of conditions such as breast cancer, skin cancer, gynecologic cancers and gastrointestinal cancers. She works closely with medical oncologists, surgeons, and other providers to provide comprehensive, multidisciplinary cancer care for her patients.
She has extensive experience in several high-precision radiotherapy techniques to improve survivorship and quality of life including accelerated partial breast irradiation (APBI), LINAC based and gamma knife based stereotactic radiosurgery (SRS), proton therapy including intensity modulated proton therapy (IMPT) with pencil beam scanning, stereotactic body radiotherapy (SBRT), high-dose rate interstitial and intracavitary brachytherapy, image-guided radiation therapy (IGRT), 3D-conformal radiotherapy, and electron therapy. These treatments may be used for a wide range of benign and malignant tumors.
Dr. Tye provides patient-centered care, prioritizing shared decision-making and evidence-based medicine to maximize benefits of treatment while minimizing side effects. Her nontraditional professional background and work across multiple regions of the United States inform a nuanced, individualized, and collaborative approach to her practice, focused on aligning treatments with her patients' goals and values.
She has coauthored numerous abstracts and peer-reviewed articles, and her work has appeared in leading academic journals such as International Journal of Radiation Oncology Biology Physics, Clinical Cancer Research and The Journal of Neuro-Oncology.
Dr. Tye completed residency training in radiation oncology at UC San Diego School of Medicine where she now serves as an assistant professor in the Department of Radiation Medicine and Applied Sciences, teaching medical students, residents and fellows.
Prior to rejoining UC San Diego Health, Dr. Tye was an assistant professor at Wake Forest University where she led the breast radiation oncology program. She earned her medical degree from University of Illinois College of Medicine. She also has a master's degree in biophysics and human physiology from Georgetown University.
Dr. Tye is an active member of several professional organizations, including the American Society for Radiation Oncology and the American College of Radiation Oncology, and research cooperative groups including NRG Oncology and Alliance for Clinical Trials in Oncology.
Outside of work, she enjoys swimming, surfing, golf, tennis, skiing, snowboarding, traveling, and spending time with her husband and two children.
UCSD Department of Radiation Medicine and Applied Sciences